Mixing silver IC with silver/copper speaker cable?

I pretty much agree with Thorman. I've tried all copper, all silver and currently run a mix of both.

Whether or not an all silver configuration will sound too bright depends on your equipment, the cables you choose and your ears. It's difficult to predict and takes experimentation to find out.

For a few years I tried a mish mash of different cables with unsatisfactory results. What helped me zero in on a sound I liked was doing a lot of research, then buying a complete set of cables from one manufacturer, then doing further tweaking. Buying all from one manufacturer may not be necessary, but I feel I chose a company that fit my taste well and it allowed me to create a "base" from which I could further refine.

Since arriving at my current set up over a year ago I've auditioned other cables, but this configuration endures.

I use Ridge Street MSE interconnects with military surplus, silver plated copper signal transfer wire (Teflon insulated) with excellent results. My speakers are mini monitors with ribbon tweeters & Bybee filters.

***

I too run a combination of both, in my case copper IC and silver speaker. It's a great combination IMO.

I do NOT believe in the theory that your system is only as good or as resolving as its weakest link. I believe that EVERY piece in your and my audio system decreases resolution and adds junk, we hope in very small amounts per piece. But that doesn't mean that improving one piece of the system can't improve the system's resolution and overall quality. Select and buy the best and most-NEUTRAL pieces you can afford for EACH position, and soon you'll have a GREAT-sounding system.
.