The posts about speaker location and room treatment are potentially valuable, but I'd still break-in the speakers first before investing a lot time with set-up, since you don't want to have to do it over again after the speakers have changed their sound. If you've ever noticed in magazine reviews, reviewers will often place new speakers in a second system and feed them a continuous signal for a couple of weeks prior to attempting to set them up for serious auditioning. Limit your variables to one thing at a time - first things first - and definitely don't rush to 'upgrade' or change any other system components or wires until the speakers are done breaking-in, as you run the risk of throwing your money even further in the wrong direction, *especially* if you wind up still not liking these speakers, in which case it will highly questionable whether it is wise to begin trying to compensate for their sound through other sysytem changes.
That question will need careful evaluation should that scenario come to pass, but it simply cannot be predictably or profitably addressed before the new speakers are A) thoroughly broken-in, and B) gotten used-to via extensive auditioning after condition "A" has been satisfied. Rushing into additional issues prematurely would be the surest way to compound the problem and stray further afield.
That question will need careful evaluation should that scenario come to pass, but it simply cannot be predictably or profitably addressed before the new speakers are A) thoroughly broken-in, and B) gotten used-to via extensive auditioning after condition "A" has been satisfied. Rushing into additional issues prematurely would be the surest way to compound the problem and stray further afield.