Help, too bright

My setup is this:
Paradigm studio 20s v2
NAD 521i cdp
NAD 320bee amp
Radioshack speaker wire
Interconnects supplied with cdp

Last night was the first time I've had fatigue from listening. Every high pitched note was unlikable. It was on a 192kbs Ravi Shankar "Inside The Kremlin" cd. Pretty much the first time I've tried to listen to an mp3 cd. Actually caused pain in my ears. Something I should mention about my speakers.. my stands are in the process of being sent to me. Ordered them last week, currently the speakers are sitting on my desk. So my questions are:

After putting my speakers on stands, will the brightness of the tweeter be gone or noticably reduced?

What speaker wires should I upgrade to for a warmer sound?

Was my cd a big factor in the brightness?

Thanks for the help.