I have been told by a designer that doing parallel single ended is not that easy to do and somewhat defeats the benefits of a simple single-ended circuit. It is hard to get twin output tubes to behave correctly in parallel and a very high demand is placed on exact matching of the tubes. A lot of SET purists also think that the operation of more than one output tube detracts from the purity of the sound of a good SET amp. I would also bet that there is more complexity and sources of sonic degradation from the additional demands on the driver tubes/circuit as well.
For something like 50 watts, one would be looking at four 300Bs in parallel--I know of only designs that work with two. There must be a good reason why one does not see four output tube parallel designs even for cost-is-no-object designs.