Would the parasound 2250 have enough current to drive the mani 2's?To the extent that the answer is predictable based on specs, I would expect it to be "yes."
The amplifier is specified as being able, with both channels driven, to continuously deliver 250 watts into 8 ohms, 385 watts into 4 ohms, and 250 watts into 2 ohms. That seems more than sufficient for a speaker recommended by its manufacturer for use with amplifiers providing up to 200 watts, that is described as having an impedance of "4 ohms mainly resistive," and that has a minimum measured impedance of 3.5 ohms.
The 45 ampere current capability that is quoted in the amplifier's specifications, btw, is pretty much meaningless, as are most such specs on amplifier current capability. 45 amps into 3.5 ohms would correspond to more than 7000 watts. Amplifier specs on maximum current capability are generally based on how much current can be delivered into a near dead short, for some unspecified miniscule amount of time, and it is therefore generally best to ignore them.
Regards,
-- Al