help me decide speakers for two channel audio

I would vote for the Wilsons. More forgiving and musical than the other two, IMHO (I'm not a big fan of Ushers). Of course, that's my preference; not knowing your musical preferences, room size, or what you're really after in speakers, as some of the others have pointed out, this is just a shot in the dark and reflects my musical tastes, not necessarily yours. I strongly suggest you get out and listen to the speakers before you buy.

Would you have room for a pair of Magnepan 20.7s, or some 3.7s plus compact sealed subwoofers?

Otherwise, given this thread's candidates so far, I lean toward the Wilson Sophias too. They're compact, near full-range, pretty coherent in presentation, and have an ease of presentation that allows the music to come to you, i.e., you don't have to strain to catch it.

Sophia it is then!!!!! As far as room is concerned I am quickly running out of room in my house with three systems already.

Another vote for the Wilsons. I had the Nautilus 802's before and thought they were very good until i heard and tried other speakers. You can get a way better speaker for the amount of money you spend on these. They are ok to look at which is about it.

I'll second the Vandersteen 5. But I would not buy a speaker of this quality with a listen first.