I guess it all depends on your money situation, because separates have more extra cost associated with them.
For example, I just went to mono-blocks. Now I have a pre-amp and two amps.
My power cords cost $550.00 a piece and interconnects cost $500.00 a pair. So an integrated would need one power cord, where I need three and a set of interconnects. So the pre-amp/mono-block set up cost an extra $1,600.00 in cables.
I also need three spaces in my rack for them instead of just one, as well as three outlets instead of just one.
The main reason that I like separates is because I have played music all of my life, and I have the audiophile 'addiction', and continually change trying to hear more and more.