Hard call sometimes, 'cause we were all obviously at zero. I personally shy away from zero-feedback sellers for bigger-ticket items, just 'cause. I also have stuff I'll eventually sell, but won't ever consider doing that until I buy a few more things and establish a higher feedback. Since I just don't do that many transactions through AGon I'm not holding my breath for that first sale...
I also prefer to not talk on the phone & give out our number - don't need any more folks knowing that number and have met enough silver-tongued devils to know it doesn't always filter out the scammers. I do prefer (semi-)local pickup if possible - I've met some truly exceptional folks that way (and y'all know who you are - every one!). I like the combination of meeting the other party and being able to see and judge the item before my money is long gone.
Bottom line is that I'd prefer to deal with someone with even minimal (and hopefully older) feedback than anyone with a zero. Not that I wouldn't ever consider it, but I work way too hard for the $$$ to send it to scams.
