It depends on how you define hassle. If you want to just turn the system on & listen w/o warm up, then tubes can be a hassle. There are some SS pieces that need warming up too, so warm up isn't a blanket statement that only applies to tubes. Then there's biasing, although some pieces have auto biasing. Then again, you might be referring to replacing tubes. The hassle factor might be the cost or frequency of replacement. Again, it depends on what constitutes a hassle for you.
I agree w/Guidocorona & especially to keep an open mind.
As for the heart & soul, again that depends on your perception. With that, I 2nd what Tgyeti said.