I think personal taste is the main factor that will determine which way to go.
If you like a tube sound, then the tube route is clearly more practical.
I've found I have limited appetite for hearing my electronics, be they hollow or solid states. I like to believe that I cannot tell the technology of my system by listening, only whether it sounds natural or not to me. I think accomplishing this with all tubes would prove to be not an inexpensive proposition.
I'm finding I like a good SS system with just a dash of tubes. I know there are other ways to achieve similar results applying pure tube amplification, but I have not stumbled upon one yet that would save me any money. Plus, I still like the low maintenance appeal of SS over tubes as well.
If the case were that I could only achieve my goals with a pair of speakers that require tubes to perform well, I would feel differently I think. But for me, the most irreplaceable ingredient in my system are the OHM omnis and these are not inherently tube friendly speakers.
The other technology that I am finding can really make the SS equation work very well and cost effectively are Class D amps.
