Liguy gives a great explanation of what the First Watt amps are about. Circling back to the original question, except for the F1 and F2, the big limitation with First Watt amps is their power output, which tops out at about 25 watts per channel, with no additional headroom, depending on model. I have an Aleph J, which is a wonderful amp, and which drives my very conventional, not-single-driver, loudspeakers to reasonable levels. Nelson Pass designs actually do sound different, and IMHO better, than many other amps. If you play music at moderate levels, you'll probably never notice the power limitation. I attached a power meter to the Aleph J and have never needed an output above 15 watts, peak. But note that my system is in a relatively small room.
I second the suggestion that you talk to Mark at Reno Hi-Fi, who can probably suggest the right First Watt amp to compliment your system.
I second the suggestion that you talk to Mark at Reno Hi-Fi, who can probably suggest the right First Watt amp to compliment your system.