Have the manual right here. Same # of per channel output transistors 64, same uF size power supply = huge .25 Fahrad (key is cap voltage rating), bias current almost identical 1.1-1.2 amps with the lower the 12e, same peak current output 200 amps (35 for the 1600e versus 70 for the 12e class A). This suggests to me that you can tap the transformer to change the voltage & I believe NP told me once it was possible for my S/550e. Ask him at diyaudio or ask Jon. If I saw one I'd buy a 12e but I think they're very rare and I've never seen a S1600e here.