McPherson, yes, without question. I went from a Carver M 1.5t amp Carver C-1 preamp to a McIntosh 7270 SS amp to the Carver C-1 pre then tried both amps hooked up to my current Cary SLP98P tube pre. The pre made a difference with the SS amps and so did the amps, then I hooked up a Cary V12R tube amp to the Cary tube pre, and heard a big difference, and an even bigger difference when I hooked up my current Cary CAD120's tube amp. Thursday, I'll be getting some (8) matched Gold Lion KT-88 tubes to find out if they will make a difference instead of the stock Electro-Harmonic's.