Hey Jamo1, try it, and if you don't like it, try another speaker. I run my JBL S4700s (which have horn compression drivers for the mids/highs) with a Bryston amp and preamp, and the results aren't too bad at all. What you might wanna try is tubes on the mids/highs and the Bryston on the woofers. That could very well be the ticket. Also, the JBLs are rated up to 300 W, and to get those woofers moving you need power, imo. I'm not too familiar with Klipsch so I can only go by specs. According to Klipsch, it can handle 400 W peaks, so the Bryston would be ok. You probably wanna put them on stands since they're only 35" tall.