For me, recordings that are highly compressed are very fatiguing, regardless of the fact that I may love the music. Unfortunately I can hardly tolerate listening to these recording on any combination of my home audio rigs. They sound fine in my car......
Bingo!
That would be my answer too.
I would add that "they sound fine in my car" means that they will also sound fine on many forgiving and "scooped midrange" type systems (these type systems are common/popular these days precisely because of the preponderance of hyper compressed audio being put out by major labels - you need a forgiving speaker to compensate for harsh CD's or iTunes downloads - google "Loudness Wars" )
Unfortunately, ATC is not forgiving and does not have a scooped midrange. These are primarily designed for accuracy in a similar manner to their big studio stuff - I think you will indeed find ATC's will be more fatiguing than other forgiving designs and, of course, your car stereo.