Hmmm, pardon me but IMHO,NOT ALWAYS THE CASE! It depends on the design of the circuit. In preamps, maybe but in amps not always.
For example, you have a 45 SET amp whose output tube Power Dissipation (Pd) is operating at 10 Watts maximum rating (as specified by RCA receiving tube manual) using a 5Y3's. What do you think would happen if you use a 5V4?
5V4, tube voltage drop is 25 volts at 175 ma. max I=175 ma.
5Y3, tube voltage drop is 60 volts at 175 ma. max I=125 ma.
Good bye 45 tube!
One way to identify the tube is to post a pic showing the plate structure of the tube. Most of the time, the 5V4's in ST bottles are flat plates. Also, you can use a magnifying glass to look for any trace of the faded markings on the tube, usually for RCA, the mark is directly in line with the guide pin as you go up on the glass.