i-tunes and Vista

A question for you all:

I am running 1.5 TB of.wav files (2TB RAID5 server) with Windows XP, i-tunes and a USB DAC.

I need to add more music storage. If I upgrade to 4TB RAID5 I'll need to convert to Vista to avoid the XP 2TB limit on disk size.

The question is:

Are newer versions of Vista as compatible with i-tunes as XP?

I can't risk any degradation of the great sound qulity I have now.

Other system components incl AudioNote 2.1 DAC, Macintosh 6500 and 402 amps, Vienna Acoustics Beethovens, VA Walz's and REL Subs, Slate cables, Audioquest interconnects, etc.

Any help with the Vista i-tunes question will be much appreciated!

Thanks,

henryisland