I would be very careful if you plan to monkey around with your loudspeakers' driver mounting screws. Most higher end speaker manufacturers understand the importance of mounting screws, especially with regards to equal torque and loosening over time. As such, the better manufacturers torque them correctly at the time of assembly and may even add a little thread lock to keep them from loosening away from their original torque.
Some food for thought:
Regarding the higher end loudspeakers, just as strong an argument can be made for leaving well enough alone. Once the screws have been "seated" at the time of assembly, it may not be a good idea to break the screws away from their seated position. The integrity of the screw hole may suffer and you may end up with a connection that always needs adjustment from that point on.