I’d spend most of my time and budget on the finest pair of speakers that floats my boat and works with my room and whatever treatments it will have. Then would pursue proper amplification for them with the features you want. It’s too subjective and proprietary to your situation to make specific recommendations, but odds are good it’ll be brands that the main stream aren’t overly familiar with. I'm partial to good tube electronics and/or tube/SS hybrid bi-amp situations, and great midrange with clarity and convincing soundstage...your tastes may vary, but there's no reason to settle for anything you don't love.
Select music sources and cabling that will play well with the speakers and amplification, and that you’ll be happy using.
You’re smart to be planning in advance.