Cable management....crossing at right angles or

Randy @randu 

Try these, I found them to be quite effective in isolating IC from PC cables. 
https://shunyata.com/products/accessories/df-mini-cable-elevator/

You are worrying too much about this! there is a difference between being neat and being obsessive for no reason, unless of course you are having a problem that you have not mentioned. Take the lid of your pre-amplifire and look inside for some aspiration. There are a number of steps you can take to untangle the mess but I think you already know what to do!

If you are using good shielded power and speaker cables, it is unlikely you’ll hear a difference no matter what you do.  If you are using stock power cords and and zip cords as speaker wires, that’s another story.

All the best.

@ghdprentice 

I do know it is low on the totem pole of audio tweaks, but my anal personality can't just forget about it. Every time I sit down to listen, I know it is lurking in the background. I can almost hear it snickering at me during the quieter moments.

Use shielded cables, keep them away from each other as much as possible, cross them at or close to right angles when you can, and then don’t worry any more about it unless you have a specific noise issue.  If you feel better lifting them off the floor, use whatever works for you.  I wouldn’t spend a bunch of money on that stuff, although years ago when I used to believe the advertising I read, I did buy a set of Cable Elevators.

An inexpensive alternative that I find to be handy is to cut pieces of foam pipe insulation, which you can use to provide separation between cables that are crossing each other or even to elevate cables off the floor, but not very high.  I usually cut them about 2-inches long and use the pre-cut slit to insert the cable in the middle.  Using one on each crossing cable and resting them against each other provides almost an inch of separation.