Do speaker cables need a burn in period?

To be ahead of its time. Yes.

Just wonderin'...

Anyone with experience with CRYOed cables - i.e. do they require more or less cookin' and burnin' ?

100% believe that any new audio equipment needs some hours to settle into its "groove" before sounding its best.Same as new cars dealers tells you to keep it simple for xxx amount of km then you can open it up.Yes Im comparing mechnical to electrical products but from the decades I spent in audio not counting the $$$ I spent I notice a improvement as the equipment breaks in.Can I prove it.Of course not but from personal experience it takes about 200 hours before the changes stops.

 Im comparing mechnical to electrical

Actually there is nothing different from "mechanical" and "electrical".  They are all made of electrons, protons, neutrals and so on.  We human beings are guilty of such categorization that leads to falsification.  Mechanical and electrical "break-in" is just the same in term of atoms or molecules aligning themselves.

I read somewhere that soaking your speaker wire in cat urine for 24 to 48 hours will eliminate the need for "burn in".  Something about the pheromones in the urine acting as a catalyst that causes the copper to deionize allowing the copper atoms to perfectly align in a way that provides purer harmonic resonance.  Be careful not to let them soak for too long though, otherwise they begin to produce an annoying hiss.  

Actually, I didn't read that.  I just made that up.  Some guy probably read as far as "hiss" and is now enthusiastically squeezing his cat over a bucket.  

Kidding aside, if speaker wire "burn in" is really required, wouldn't it make sense for the manufacturers to "pre-burn" the wire before shipping?  Seems like it would be a fairly easy thing to do and would prove to be good selling point.  They can even pre-burn it based on musical genera.  The blue spool was pre-burnt with smooth jazz, the red spool with classic rock, etc.  Just a thought.