If you look at the configuration the tweeters are in the center... they are made to be placed horizontally. You would need to elevate them a couple feet to have the tweeters at ear level as they should be. then all the bass drivers are all at ear level... not sure what the SQ implications are.
It might work. I would only try it if you get an extended home listening with option to return. These are very fine speakers, purpose designed. Using them in a different configuration is unlikely to be optimal. I have SF Amati Traditional and can tell the difference between small changes in toe in. I highly recommend the brand, but would look at the Olympica Nova.