So, lower plate load is better, from what I'm hearing you say, and this is because it's easier on the amp, less current to control, less heat to wield?@listening99
Not in this case- the reason I would go with the 7581/6L6 is that apparently the output transformer is set up so that it presents a reasonable load to a variety of power tubes, each of which work best with different impedance. Since the KT88 wants to see a higher load impedance, this means that the transformer is probably loading the 6L6 at that higher impedance too.
Now transformers are called that because they transform impedance, but that works both ways. So if you put a lower impedance than 4 ohms on the 4 ohm tap, the power tube will see a lower impedance too. But if the power tube is normally seeing something that is a bit higher than is optimal (for power output reasons) when the speaker load is lower the amp will respond by putting out *more power* which is actually what you want it to do when that lower impedance (3.1ohm dip) is encountered. So the 6L6 will allow you to do that, while the KT88 probably will be less likely to do so (and also will make higher distortion).