I think I am almost there with my system, although I fear that audio nirvana is really a journey, and never an end game.......
I currently have a Lexicon MC-1 processor, Krell KPS28c-cd player, Sony dvp-9000es dvd player, Magnum Dynalab Etude FM tuner, B&W Nautilus 801 as main L/R speakers, Nautilus HTM-1 as center speaker, Matrix 801 Series 3 as L/R surround speakers, Krell KAV-1500 5-channels @ 300watts/channel amplifier for the main L/R (bi-amped) and center speakers and Meridian 557 2-channel @ 200watts/channel amplifier for the L/R surround speakers.
I use PS Audio Power Plant 300 for source equipment and Audioquest Python for all interconnects, and Slate speaker cables for the main L/R and center speakers and Type 4 cables for the surrounds. For power cords, I use Shunyata Black Mumba, Cardas Golden Reference, and Audioquest AC-12 and AC-15.
I am toying with the idea of getting a Krell KCT pre-amp to round out my 2-channel audio.
Hopefully, with all this, I think I will find my audio nirvana....for the time being I think...... or until I emerge from financial bankruptcy from buying all this equipment.