Sounds more like a problem with your amp. It doesn't make sense that you can't adjust the bias. Swap 2 tubes and see if the problem moves to the new location. report back.
Now when you say the other 3 move "all over the place" are you saying that they respond to bias adjustments?
Bias at 25 vs 35 is hardly noticable sonicly, especially if 3 of 4 are set correcty. Thus the sound is good.
Jerry