I noticed a significant improvement when I rolled the tubes in my ARC VT100mkII, but it was no walk in the park. Replacing the power tubes was simple enough. I would definitely recommend the Svetlana KT88s over the stock Svetlana 6550s: they will provide you true tube warmth and liquidity. For about $500 more you can buy premium tubes, but you need two matched quads and replacements may be difficult to find. Thetubestore.com will sell you the matched number-coded Svetlana KT88s, so buying replacements is not a problem.
When I tried to roll the four pairs of driver tubes, I blew up one hell of tubes and resisters. Chris at Audio Research told me I should not attempt to replace the "stand alone" pair of Sovtek 6922s located physically towards the amp's front end with any other brand, as the amp cannot be properly biased without them. But I had already found a tube that would perform in that position and not blow stuff up -- the Mullard CV5358. And I had done enough experimenting to know I didn't want the Sovteks, which in that position really limited what the amp could do. Bought the Mullards NOS from Michael Wharton at Brit Audio. While the amp can be biased around the Mullards, and their huge soundstage is a big improvement over the Sovtek's rather lifeless image, they are lush to the point of sounding mushy. Matching them with three pair of relatively clincal/analytic sounding Amperex 6DJ8s (orange globe logo, Holland, steel pins) did the trick.