Dan,
Since you ask, my wife and I gave the Tempur-pedic mattress a go, and I found that after two days my back was killing me. She sweat to death because well, foam doesn't breathe all that well, and she woke up in the middle of the night looking like a freshly boiled lobster. So did we walk away from the challenge of making it work with the mattress? Heck no! We litz wired some Cyberlight IC's through the center section of the mattress for added support with the added benefit of nocturnal light therapy, plugged one end into a dark, personal place and the other into the back of our DK, ran the amp with some NOS Mullards, and let me tell you...well, I'm sure you can guess...but suffice it to say that my wife's midrange had that 'you are there' feeling in no time at all. This audio stuff is simply dreamy!