With most of the speakers in my house, including the OHMs and Dynaudios which are not inherently tube amp friendly speakers, moving from the lower Damping higher output impedance amps I mentioned to others with damping much grater than 50 produced perhaps the biggest sonic benefits of any change I recall in recent years.
Those same amps played very nice with my more tube amp friendly Triangle Titus XS speakers for which I would like to find a nice small easy to maintain tube amp. I use the Triangles also with my highly damped Bel Canto ref1000m Class D amps and the sound is quite good still in many ways (crystal clear especially at lower volumes) though somewhat sterile at higher volumes in comparison to the others that are a better match to that amp in regards to impedance and damping.
So I have found that damping/output impedance matters VERY VERY MUCH, perhaps as much or more than many other also important things. Understanding this has been a key for me to getting to a good place faster with fewer stumbles along the way.
Beats playing with fuse directions by a light year IMHE of course that is a much easier thing to do right being there are only two choices, more like answering a true false question that has no right answer other than what you think and/or hear.