Ok, scenario:
two systems, same speakers (energy rc-70's)
McCormack DNA-750's upstairs, Yamaha CD player, sanders preamp
basement: carver 600 sig, b&k pro 10 mc (newer looking one), some old Sherwood 6cd changer.
the monos sound better after being on for over 24 hrs,
carver is absolutely no lsouch by by any means. But when it comes to peaks, and drum solos, I feel the carver has a little more oomph to keep the depth and in your face sound right there, the mccormack's are better at detail and decay, hidden vocals, fadout sounds. They each have their flaws, and extraordinary attributes.
In the end, and yes I have mix and switched gear all the time. But the upstairs has a 18 foot vaulted ceiling,making it harder for the little rc-70's to fill the room, while basement has absorbing ceiling tiles, about 8.5 feet, so the sound is more vivid in basement than upstairs. due to the area size.
Too many variables to say to say what is best. Use your ears to be sure.
Mono's have been the rich mans audio, for bragging rights.
Nothing wrongwithanicekiller stereo amp, there are a shite load of them
Happy hunting