Dedicated 20 amp lines/should i use a sub panel

It is good not to introduce additional wiring and contact points, but...

it is also good to isolate the whole thing from any noise that reaches the main panel and a sub-panel could help with that.

I ran 2 x 20amp runs on 10 gauge from 2 side by side breakers for monoblocs. I ended up not using one of them because of a hum loop. Let us know how you get on.

I don't think there's a big benefit, besides wiring alone, but there are some interesting options in terms of noise suppression and balanced power at the power panel.

Check with your electrician.

My electrician recommended a subpanel and I'm so glad I went for it. His reason was my main box was a mix of old and new wiring and I was hearing noise thru my existing line to my Hifi rig.

He knew what he was doing since now I have two separate runs with no metal staples used, with two Hubbell receptacles grounded at the subpanel. He also added a second 8' grounding rod.
There is absolute silence thru my speakers now, and I'm using all tubes. I was able to remove one of my power conditioners since the noise floor is so low.

 

I believe we need to hear from some of our more experienced professional electrical experts here on Audiogon (you guys know who you are).
I'd also really be interested in knowing if there is or isn't an advantage to using a sub-panel if there are openings in the main panel?
No offense meant to those that have answered above.
I also use a sub-panel in my systems.