Now here it comes. There is a tendency for people just to chime in with their own speaker with the opinion that "they are the best speakers, period". lol. Speakers are a very personal choice and not every speaker is the right one for every person. I personally do not like the Wilson signature because I feel it is slightly too thin and overly clear sounding - almost like "turning up the sharpness on video too much". That's my own personal opinion, but based on what you said you are looking for, the "Wilson signature" may be what you want.
Focal speakers are very clean and fast. However, for me, they just seem too thin overall (not enough body/thickness -- even in the bass). The beryllium tweeter is crystal clear, but I noticed that it introduces a "bell like" character to all tones. I'm sure many people love Focal, but it is not for me.
It's unfortunate that you said speaker weight is an issue. If you are looking for strong bass, you have to accept very large/heavy cabinets and drivers. You could do a subwoofer, but the fidelity may not be what your looking for. Maybe look into REL subwoofers. They tend to blend very well with audiophile speakers.
The Wilson Sophia 3 is about 165 lbs per speaker. That is a sign of good cabinet construction (cabinet that is resistant to resonance with good bracing). The Sophia do have wheels so moving them around is easy, but you would need help with getting them up/down stairs. The Sophia is 89db efficient, which is pretty good for an audiophile speaker (typical is 86-87). As I said, they require high current amp. A 100 watts per channel is somewhat lean in my opinion, I would recommend 200 watts minimum. The Parasound JC1 are 400 watt monoblocks, but something like Parasound A21 would be minimum. I do not have experience with tube amps, so I could not advise on what would be good.