Having played around a bit with my own speakers I can suggest if you go ported use some interior wall lining and minimal stuffing. You want to retain the 'life' but still decrease back reflections through the cone. That's a tough balance to find.
Also if port use two ports for each speaker it seems to work better for a larger driver. Don't be tempted to tune the Fb too low. That driver you may find a tuning of anywhere from 45hz to 52 hz works better in that size cabinet than something lower. ymmv.
Build the cabinet so it's somewhat easy to pull the back off or the driver out to make adjustments.
There are some great modeling programs available. They can work well I think- but in your room it really may boil down to trial and error once you have it fairly close by spec.
Cheers,
RW