I like AN-E's that you mentioned and recommendations for the Spendor SP100. I don't know what price range you are looking at, so as a broad mention of speakers that will probably work well with 50 watts, the following brands are worth looking into:
1. Tekton (I heard their $3,000 model at a show and it sounded quite good.
2. Charney Audio--I've heard a $13,000 and a $17,000 model (same speaker with different full range driver) and both were VERY good, particularly the $17,000 model with the AER 3 driver).
3. Rethm Bhaava--this is a $3,000 speaker with a wide range driver and a built-in powered subwoofer that sounds great for the price.
4. ProAc--I like a number of models in their lineup. Although not that high in efficiency, their speakers sound quite good with modest power--must be easy to drive. I particularly like the big D48R floorstander and the D2 stand-mounted speaker.
5. DeVore Gibbon X--perhaps not as low-power friendly as the O 96 Orangutans, but I heard them with a 30-watt Luxman integrated and the combination sounded quite good.
Good luck in your search.