Since you have space issues and you realize the Vandy's may need some room to do their magic it would seem you've answered your question.
There is a lot to be said for Meridian gear but as sensible as they may be Vandersteens simply make music. The attention to time and phase that goes into all Vandersteens blows away many other fashionable designs. You may notice that real audio improvements are rare which is why some designers can maintain a customer base without evolving a new model every year or two.
My suggestion is to get the Vandy 5's or the Quatros, empty your room, dial in the speaker/room relationship, then backfill with your stuff. Otherwise why waste your money on high end speakers then set them up in a mid-fi environment?
There is a lot to be said for Meridian gear but as sensible as they may be Vandersteens simply make music. The attention to time and phase that goes into all Vandersteens blows away many other fashionable designs. You may notice that real audio improvements are rare which is why some designers can maintain a customer base without evolving a new model every year or two.
My suggestion is to get the Vandy 5's or the Quatros, empty your room, dial in the speaker/room relationship, then backfill with your stuff. Otherwise why waste your money on high end speakers then set them up in a mid-fi environment?