Good OTL's are astonishing in the way they deliver a lively, immediate and vibrant sound. But, as Jsautter mentioned, most require a speaker with a high and/or flat impedance curve because the output impedance of these amps are high (the only way to reduce the output impedance of an amp without a transformer is to parallel in more output tubes).
The other issue is that there are so few available that one has limited options in terms of voicing. I like the Atmasphere amps, but, they are on the somewhat lean side, so they may not voice properly (for my taste) with speakers that are on the leaner side. For example, the Devore O/93 or O/96 are on the warmer side and they do tend to be a bit sluggish sounding so the M-60 might be an ideal combination. Would that be the case with the Devore Gibbons (a leaner sounding speaker)? Who knows, one just has to try the combination.
The other issue is that there are so few available that one has limited options in terms of voicing. I like the Atmasphere amps, but, they are on the somewhat lean side, so they may not voice properly (for my taste) with speakers that are on the leaner side. For example, the Devore O/93 or O/96 are on the warmer side and they do tend to be a bit sluggish sounding so the M-60 might be an ideal combination. Would that be the case with the Devore Gibbons (a leaner sounding speaker)? Who knows, one just has to try the combination.