A whole house surge protector is nothing but a bunch of large MOVs put across the AC lines (and to ground which is also important). This is not a bad thing, this is a good thing. It will have no impact on the sound at all. Schneider/Square-D, Eaton and any number of well known and reputable companies make these. They are relatively inexpensive, but there are larger and smaller ones. If you are in a lightning prone area, go for the big one. It is not going to survive a lightning strike right next to your house, but can survive one in the neighbourhood.
The good thing about putting one at the panel, is then you have the inductance of the AC wires from your panel to your equipment to soften the spike. I would like to think that any competent piece of audio equipment, especially really expensive equipment has some level of built in surge protection as well. The combination of the whole house and the in-equipment is likely to get you through most anything.
Simple power bars with simple surge protection will put more MOVs across the line. Being at your equipment, that is going to help even more. Some basic power bars add some inductance, which will help more, but that will add impedance to high current draw. Some devices will go even further with larger inductance and circuits after the inductor and provide (in combination with your whole-house protector), protection for just about anything, but it does increase impedance between the AC line and your equipment. You can decide if there is any sonic impact of that or not.
The good thing about putting one at the panel, is then you have the inductance of the AC wires from your panel to your equipment to soften the spike. I would like to think that any competent piece of audio equipment, especially really expensive equipment has some level of built in surge protection as well. The combination of the whole house and the in-equipment is likely to get you through most anything.
Simple power bars with simple surge protection will put more MOVs across the line. Being at your equipment, that is going to help even more. Some basic power bars add some inductance, which will help more, but that will add impedance to high current draw. Some devices will go even further with larger inductance and circuits after the inductor and provide (in combination with your whole-house protector), protection for just about anything, but it does increase impedance between the AC line and your equipment. You can decide if there is any sonic impact of that or not.