Hi all. I'm new to Audiogon and have done more reading than writing. I tend to believe (would that qualify as IMO?) that a well designed speaker will perform well, more or less, in a wide variety of rooms. The better the room is for sound quality the better that speaker will sound. And of course, what you kit is comprised of plays a role, too. More importantly, enjoying the music, with the kit you have and in the room you have, is what it's all about. Of course, tweaking and tuning to within what is realistic in your life, goes a long way. Much better than ignoring the room altogether. But, enjoying the music is surely what it's all about. Back to a well designed speaker... I do like the approach that Dynaudio takes. They make wonderful sounding drivers, all engineered and manufactured in-house, providing them with the ability to control the end result in a superior way than many other speakers brought to market. Then, they engineer the given enclosure for those drivers from a total "system" approach to the finished product. This includes engineering the front baffle for directionality and, therefore, room interaction = acoustics at your ear.
Anyway, that's my two cents on this matter. There are many wonderful products on the market. Make your kit, work with your room the best that you can, and enjoy the music.