Do you like your speakers aimed directly at each ear or....

Depends very much on the speakers and the room. 

Focal's tend to be designed to be flat to the wall behind them. 

In a narrow room, pointing the speakers so they cross in front of your head may minimize early reflections.

My Vandy 2CE Sig I’s are almost straight ahead with very very little toe-in. Provides the best soundstage and imaging.

Really, all speakers are different. 

Think of your toe-in angle as a treble level control and an imaging control. Straight ahead to start, then dial in gradually to get the right tonality (clear and detailed but not too sharp) and image specificity (image wide and deep, objects distinct side to side, front to back not too diffuse and confused).

Depends on room and EARS. I have found the 1 or 2 inches can and does make a difference.