Does high end system with dedicated circuits need grounding products

I have cryogenically treated and TC coated 4 ga wire bring 240V to a step down, then 120V to my conditioner. So the system is transformer isolated, with its own earth ground connected to a grounding block on the conditioner. https://systems.audiogon.com/systems/8367 

The Synergistic Research Atmosphere Level III interconnect comes with grounding clips. The included grounding plug is nothing more than a good quality three prong plug with just the 2 grounding wires connected to the ground pin. So I removed the plug and connected the wires direct to my grounding block. Talking with the Cable Co back when I was buying the IC they said that's all the fancy SR block is, a very attractive looking bolt and nut job, no special sauce or circuits.

So I don't know for comparing but no reason to think what I have is any better or worse than the SR grounding block.

Which is.... a small but noticeable lowering of the noise floor, a little more delicacy and a little less grain. But not much. Worth plugging in if you have it. Not worth what they want for the box. Although for that kind of money its hard to believe they wouldn't put a dab or two of the stuff they paste on fuses and outlets that makes them so much better. If they do, and it makes the grounding block quite a bit better, it just might be worth it.

Active may be quite a bit different. Would love to try one, if I didn't have so many more things on the list of things to try.

+1 to Mike’s excellent answer and description of what a solid and beneficial system tweak/enhancement can be had from employing these system upgrades. IMO, the first step would be dedicated lines and judicial listening. If more improvements are thought to be warranted then you should explore similar products to those you have already listed. Just make sure to listen and measure at each step to determine if the added pieces move you in the right direction to achieve your end goal. Test and measurements rules the day. Some of the reported improvements will always be system dependent and some are cleverly disguised “film-flam” (a highly technical term 🤔).  YMMV.

I have the SR active ground block with the better ground wires and orange fuse.  I also have the 12-outlet power conditioner UEF-SE and a black outlet. I have a dedicated 8 GA wire line. Like Tom said, your mileage may vary. In terms of improvement, the conditioner has the better ROI, followed by the dedicated line. Cannot say much about the orange fuse in it as I have not tried swapping it. The active ground block is the least as far as return on investment is concerned. This is in my system, might be different in another one. Hope that helps. 

I just installed the Nordost QX4 and QBase 8 and am very happy with it. It made a noticeable improvement in my sound

I also have Frey 2 power cables throughout my system. Quality power cables make a significant difference as well. My experience has been that consistent power cables and interconnects help balance the system. Obviously power conditioning plays a big part. Since going to complete Nordost cabling in my system, along with their power conditioning QX4 I have witnessed a smoother deeper sound. Hope that helps