Really impressed how the RME sounds going direct, bypassing a separate preamp.Yes 9 times out of 10 going direct is a clear winner, with better transparency/detail/pin point imagining, tighter deeper bass and better dynamics.
But "if" your system has problems somewhere with harshness/hardness, then sometimes it "can" be accentuated by going direct, then the right preamp colouration may put a bandaid fix on these and colour/soften them so they’re not so obvious.
Cheers George