Mijo, Just to be clear and as I said the first time, I was not talking about "emboli"; I was talking about "microthrombi", tiny clots that occlude the capillaries that run in the alveolar septal walls and which are needed for oxygenation of blood. Those microthrombi are caused by direct virus infection of the endothelial cell lining of the capillary. Injured cells then release clotting factors locally, resulting in clot formation. This process is rather unique to COVID. The mode of death in COVID very often involves the generation of these microthrombi on a massive scale throughout the lung, such that the patient does not have the alveolar perfusion necessary to maintain life off a ventilator. Patients with COVID can certainly have classical pulmonary emboli, as well.
Like you, I also am not "convinced" that the (RNA) vaccines give more solid or longer lasting immunity to disease; I tried to convey the possibility that that "may" prove to be the case. Seasonal coronaviruses do not induce lifelong immunity to seasonal coronavirus diseases, and so it is possible that persons with COVID will not be protected lifelong from COVID. (Note, I am talking about clinical illness, not infection per se.) If the RNA vaccines induce effective memory responses, it is at least possible that long term protection will be as good as or better than natural infection in protecting from future disease. However, there is no way to know at this time. In 5 years, we will know. The reasons I say what I said about the RNA vaccines vs naturally acquired infection are complex, would take a couple of paragraphs to explain.
I do agree it seems that getting COVID twice (over the short history of the disease) is at least very rare. That’s why I wrote earlier that we probably don’t have all the facts straight regarding Peter L. Also, every documented second illness due to COVID that has been reported in the literature was LESS severe than the original disease in that person, except for one report that I can recall. So if PL is having his second illness, and if it’s worse than his first, he is in a very rare category for sure. There is a better chance that we don’t know all the facts.
Like you, I also am not "convinced" that the (RNA) vaccines give more solid or longer lasting immunity to disease; I tried to convey the possibility that that "may" prove to be the case. Seasonal coronaviruses do not induce lifelong immunity to seasonal coronavirus diseases, and so it is possible that persons with COVID will not be protected lifelong from COVID. (Note, I am talking about clinical illness, not infection per se.) If the RNA vaccines induce effective memory responses, it is at least possible that long term protection will be as good as or better than natural infection in protecting from future disease. However, there is no way to know at this time. In 5 years, we will know. The reasons I say what I said about the RNA vaccines vs naturally acquired infection are complex, would take a couple of paragraphs to explain.
I do agree it seems that getting COVID twice (over the short history of the disease) is at least very rare. That’s why I wrote earlier that we probably don’t have all the facts straight regarding Peter L. Also, every documented second illness due to COVID that has been reported in the literature was LESS severe than the original disease in that person, except for one report that I can recall. So if PL is having his second illness, and if it’s worse than his first, he is in a very rare category for sure. There is a better chance that we don’t know all the facts.