Seeking advice on power conditioners/regenerators

If you size the ps audio regenerator right it will improve your amps too. Conditioners are notorious for limiting amp sq and if you get too small of a regenerator you will be doing the same thing. Ps audio had an in-home trial policy so instead of guessing or asking for somebody’s opinion, get 1 and listen to it and buy it if you think it works in your system

I received my P20 in May 2020.  When I plugged most of my components into it, the sound was good but I had a hard time hearing the difference from when everything was plugged directly into the wall. The P20 was plugged into a dedicated 20amp line using a Shunyata Sigma NR 6' 20 amp power cable. 

Then recently, I watched a video on Jay's Audio Lab's YouTube channel where he compared the sound, using the P20 with the Shunyata Denali 6000 and reading a PS Audio forum post where a user claimed unplugging everything from his P20 and into the wall outlets made his amps come alive. I then unplugged everything from my P20 and plugged everything into my  wall outlets. The sound had more detail with more dynamics. The change wasn't dramatic but it was noticeable enough that it prompted me to sell my P20. 

I'm now plugging my components directly into the wall. I have 7 dedicated 20 amp lines running from my home theater to a dedicated service panel with a copper bus bar, using 10 gauge shielded wiring with Furutech GTX outlets so my power situation was pretty good before my P20.

However many people do report that the P20 dramatically changes their system for the better. Possibly the P20 is better suited for systems without dedicated lines and run appliances from the same panel while they use their system.

Good luck with your decision. 

My system:
Room is 21'L x 14'w x 12'h with 14'wx12'h floor to ceiling velvet drapes on the front wall, 10'x7' velvet drapes on the right wall and 9'x7' wall carpeting on the left wall.
4 Goldenear Triton Ones FR, FL, LS, RS
Each Triton has 4 IsoAcoustics GAIA II Isolators that are on top of a 
3" thick Butcher Block Acoustics Maple Audio Platform.
Goldenear Supercenter Reference 
Goldenear Invisa HTR-7000 In-ceiling speakers RFH, LFH, RRH, LRH
Parasound JC5 FR, FL channels
2 Parasound A51 All other channels 
Marantz AV8805 Preamp Processor 
Oppo 203 
LGOLED77CX
Audioquest William Tell Zero Full Range Speaker Cables 8' each to FR, FL, C
Audioquest  Type 5 Speaker Cable to all other channels except for the LS that uses Amazon speaker cable.
DH Labs Silver Sonic HDMI cables for Oppo 203 and LG
Audioquest Water XLR cables from Marantz to Parasounds for FR, FL, C, RS, LS
Audioquest Red River XLR cables from Marantz to Parasounds for all 4 height channels. 
Audioquest Firebird high current 3' power cable for Oppo 203 
Audioquest Hurricane high current 6' power cable for JC5 
All other power cables Shunyata Venom high current 6' 
7 dedicated 20 amp lines using Furutech GTX (R) NCF outlets and Furutech outlet covers, 10 gauge shielded wiring to a dedicated panel with a copper bus bar. Unfortunately the panel is about 20 feet away from the outlets. 

Yes. No. Maybe. Depends. 

We have poor power and for here an audioquest helped. 

Like so many say your ears will decide. 

Thrre’s a reason(s) so many mid to higher end systems treat power. It helps.

Here's the thing. What are the possible sources of noise you are trying to clean up? If you live in an urban area or near any commercial or industrial facilities, you're likely to need some cleanup. If the circuit to which you power your system is shared with appliances, dimmers, florescent lights, etc., you're gonna need conditioning. If your system is composed of mid-level components that don't properly shield the noise they generate internally, you'll need help. Finally, if your speakers are high sensitivity speakers, you'll likely hear some of the noise. BUT.....If you don't have any of the above issues, and can't hear any noise in the black parts of music, you'll likely be wasting money and possibly adding problems by adding conditioners or regenerators. Don't believe the hype about improvements on problems you don't have.

J.Chip

Like anything else, you need to try one in your system. A friend who's also a dealer (audio, that is) once brought over one of the more expensive PSA regeneration units and it had no effect, whatsoever. I'd second the suggestion to try one from an online vendor that offers a free, in-home trial (free, except for return shipping), if you cannot borrow one. 
Keep in mind that Music Direct may penalize you in future if you buy something and return it. In my experience, Audio Advisor is more forgiving in this regard.