Mike, if you're using 10 gauge wire the breakers should be 20A. There's no reason to use one 15 and one 20A.
If you use 10/2 Romex, you would use two 20A receptacles for your audio.
As stated before, use a subpanel for audio. Main 200A panel will have high-current draw appliances, lighting, and household devices.
Each panel will have an 8' ground rod, check with electrician for code.