Main vs. sub panel for dedicated lines


I am building a second home on my property. Will have a dedicated audio room. I will be routing 2 or 3 dedicated lines for my audio system. The high current devices for the home will be run off the main panel. I will install a sub panel supplied by the main to accommodate power for 2 bedrooms and a 1/2 bathroom.  

Question, should I run my dedicated lines off the main or the sub panel? I could move some of the high current devices to the sub panel if needed.

Thanks in advance for advice. 
mesch
@jea48 @mesch
I have a new service panel and a subpanel. When the sub was installed, a second ground rod was added. Two different electricians installed the panels, both said two ground rods were required to meet PA code.

Edit... the 2 panels are near each other on a basement wall.

@jea48  @lowrider57  I will consult with my electrician on the amperage supply to the sub panel and the need for sub panel ground rod.

Regarding audio quality would I benefit from running my system through a sub panel that only serves low amperage devices, my amplifier likely the highest one, over running it off the main panel to which the sub panel is attached?   
SQ has been debated, but keep the audio system together on the same leg (phase).

It is cheaper by far for the electrician to just drive two ground rods and be done with it.
Exactly what my electrician said when we replaced the water main copper with plastic.