SET vs OTL


Could someone tell me the difference between a single-ended triode amp and an output transformerless amp?

Is it true that despite its operational inconveniences, a good OTL (eg Tenor Audio) will always sound more "natural" than a good SET (eg a Cary 300SE)?

Thanks
aarif
I own both SET and OTL, but most of the time i kinda just use the OTL Amps more often than SET Amps.
I have used a Graaf Gm20 for about 10 years before upgrading to a Wavac Ec300b some 10 years ago. In short, there is no going back: while the Graaf had twice the stated output power, making that power useful was challenging: using autoformers to ideally match speaker impedance as well as pretty regular rebiasing, neither of which is required by the Wavac. If anything, the Wavac is faster than the Graaf despite its transformers and the bass is substantially more solid. Botj amps are classics in their line of design
I have never encountered a SET amp that even came close to an OTL when using an OTL friendly speaker. The difference is startling. I find this true of P.P. designs as well. 


@antigrunge2,
It is interesting how people hear audio products and how it formulates opinion and decision making. Some OTLs may sound faster than some SET amplifiers. Some do not. Your experience with the Graaf and Wavac is similar to mine.Ive heard SET with as much "speed" clarity and transparency as fine quality OTLs. Some may experience "sweetened" or "lush" coloration with certain SETs but they all are not the same.

I would caution against painting with the proverbial broad brush. My SET is organic and full of tone/body, very natural and has an  emotionally engaging presentation. There is no sacrificing of nuance or natural detail. There are many variables that determine what works best for a given listener and their respective audio system. Many roads do in fact lead to Rome.
Charles
Well actually no! True the quality of the iron as well as the circuit and its design do contribute and can make significant improvement in any amp design, the absence of a transformer contributes hugely to the intrinsic difference in sound. Provided that the amplifier requirements are met, I think an OTL is a superior design. 

Antigrunge,
What speaker were you using for this comparison? 

Phantom a/v is correct in that impedance is crucial with OTLs which can be a serious impediment. Your experience mirrors mine. What amazed me was how quickly the SETs we used in the comparisons went into soft clipping. They got more muscular but confused sounding. It took hours of listening and direct comparison to figure this out.