In a nutshell, hypothetically, if the speaker is a "very easy drive without any hindrance" at all to either amp, the OTL in class-A will be the better amp full stop.
BUT!! for an OTL not to be hindered IN ANY WAY at all by todays "better sounding speakers loads" that have NOT had "their sound compromised" (because they were designed "firstly" too give a very easy load), is a big ask.
And those type of "very easy to drive speakers" usually have big other glaring problems to many listeners that are susceptible to their colorations, so it’s a bit of a catch 22.
Cheers George