The room had its own dedicated power subpanel, and the lighting was supposedly on a completely isolated line.The operative word being, "supposedly"!
For the "I've lost count of how many times" time, there is no such thing as a completely isolated line. The closest you can get is batteries. Even then the batteries must be disconnected from the line. Even then the isolation is only partial, because RFI is everywhere. You want a completely isolated line, build your house inside a Faraday cage, with its own nuclear power plant. With just the stereo. No lights. No nothing. And with the power plant somehow isolated......
Short of that: there is no such thing as completely isolated!