I run Qobuz using an ASUS ROG (Republic of Gamers) laptop using Windows 7. I connect the laptop to my PS Audio PerfectWave MkII DAC with a regular (not expensive) USB cable. I also have a PS Audio PerfectWave Transport (I have several thousand CDs). The core of my system consists of Krell preamp an amp plus a pair of Thiel CS6 speakers.
I have compared at least a dozen CDs with their corresponding Qobuz stream to determine the difference in sound quality. I've been careful to make sure that the CD and the streaming file are the same version. In all cases the stream sounds virtually identical to the CD. Sometimes I think I can hear a very slight difference but in practical terms they are the same. I seriously doubt if I could tell them apart in a blind test. Just for the record, I've ripped my CD collection and I've also compared ripped files played through the PC using Foobar to their respective CDs and the Qobuz streams. They sound essentially identical.
One reason for this may be that the PSA PW MKII fully buffers and reclocks the incoming data. This step should eliminate any noise or other nastiness from the sound.
This result was a surprise to me. I figured that I would surely get a high quality streamer but now I'm taking my time. I'm probably going to spring for a Node but it will be mostly for the operating system and convenience.
If you don't have a CD player then it will be difficult to judge the sound quality of whatever you do. I firmly believe that in order to judge the sound of new components you need a control. Using a CD player as a control will help you to figure out if a streamer really sounds that much better than a computer. I honestly believe that we all hear amazing things when we spend thousands of dollars on a new piece of gear but often with careful controlled comparison those "blew me away" differences become very minor.