I'm surprised no one has suggested the Rogue Cronus Maxum III integrated tube amp. It's $3K (new) and has more than enough power to drive the Klipsch Heresy's even in your (fairly large) room. I have no personal experience with this amp but my closest audio friend, whose ears I trust implicitly, loves his.
I've heard that Rogue with Magnepan 20.7's and it sounded VERY nice.
Sean from Zero Fidelity has said multiple times that his Cornwall's with the Luxman is a system he could be happy with for a long time.