Lots of words in this rant from about 2009, and worth reading it all at one’s leisure.
In the meantime, this is the relevant message, about half way down just above the picture of the tube on the left -
This is why the CV181Z might not be a drop in replacement for the 6SN7. Typical 6SN7 heaters draw about 0.6A and the CV181z draws about 0.9A (900mA), the old Mullard CV181 drew 950mA. This 50% increase in heater current amounts to 0.6A for a pair of CV181 in a circuit, which as you can see represents the load of a whole extra double triode.
I’d be more decisive. "This is why the CV181 (Z, whatever) IS NOT a drop in replacement for the 6SN7." Eventually your amp will take up smoking.